Blood clots are a huge burden on healthcare systems across the world, make sure you are up to date by testing yourself on this set of questions!
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Stem 1, question 1 of 4
Colette, a 35 year old, presents with 3 episodes venous thromboembolism in the last 12 months
Which of the following does not increase the risk of venous thromboembolism?
Factor V Leiden
Stem 1, question 2 of 4Collette is diagnosed with Factor V Leiden, why has this genetic disease been selected through evolution?
Provides resistance against malaria
Provides resistance against cholera
Reduced risk of breast cancer
Increased viral immunity
Reduced bleeding tendency postpartum
Stem 1, question 3 of 4Upon further questioning, Colette reveals she has had 6 miscarriages over a 10 year period. What disease encompasses both a tendency to thrombosis and recurrent miscarriages?
Protein C deficiency
Protein S deficiency
Disseminated intravascular coagulation
Stem 1, question 4 of 4Colette is given heparin but has a prolonged bleeding episode, what is the reversal agent for heparin?
Stem 2, question 1 of 6
Clementine, 24 year old female, presents with a sore and swollen leg. She has recently returned from Singapore on a business trip
What is the most likely diagnosis?
Deep vein thrombosis
Ruptured popliteal's cyst
Stem 2, question 2 of 6Clementine takes the oral contraceptive pill. Which of the following is not an effect of the oral contraceptive pill on coagulation?
Increased plasma levels of I
Increased plasma levels of IX
Increased plasma levels of X
Decreased tissue plasminogen activator
Stem 2, question 3 of 6Another inherited cause of venous thromboembolism is anti-thrombin deficiency, what is the inheritance pattern of this deficiency?
Stem 2, question 4 of 6A few days later, after her leg pain has settled, Clementine becomes very breathless and is diagnosed with Pulmonary Embolism. Describe the local of the oblique lung fissure.
Runs from the superior border of the lung in a inferoposterior direction
Runs horizontally from the sternum at the level of the 4th rib
Runs from the lateral border of the lung in a superoposterior direction
Runs from the inferior border of the lung in a superoposterior direction
Runs vertically from the sternum at the level of the 4th rib
Stem 2, question 5 of.6Clementine is given warfarin for her pulmonary embolism. Which of the following drugs must Clementine not take?
Stem 2, question 6 of 6What is the use of a D-dimer in combination with a Wells score for Deep vein thrombosis of less than 2?
A positive D-dimer rules out a deep vein thrombosis
A negative D-dimer means a deep vein thrombosis is very likely
A positive D-dimer means a deep vein thrombosis is highly likely
A negative D-dimer means a pulmonary embolism is highly likely
A negative D-dimer rules out a deep vein thrombosis