This quiz tests how well you understand the management of alcohol withdrawal, opioid toxicity and some basic psychopharmacology of other addictive substances.
Reviewed by: awaiting review
Stem 1 - question 1 of 4
You are a final year medical student joining the local ambulance service on a night shift. You are called to an alleyway where the police have reported finding a semi-conscious male who they suspect has had an overdose. When you arrive, you find the patient in respiratory depression and with pinprick pupils. A tourniquet, used syringe and bent spoon are found by the patient.
What drug would you administer to reverse the effect of the overdose?
Stem 1 - question 2The patient is stabilised and moved to the ambulance. After treatment with the coma cocktail the patient starts to come around and the paramedics decide to transfer the patient to hospital. En route, the patient starts to show signs of opioid withdrawal. Which of the following are possible signs you might observe? Select three answers.
Stem 1 - question 3Which of the following are used in the management of heroin addiction?
Stem 1 - question 4Buprenorphine is an alternative to methadone in the first line treatment of opioid toxicity. Which of the following is true of buprenorphine?
Buprenorphine is cheaper than methadone
Buprenorphine acts faster than methadone
Buprenorphine is a full mu-receptor agonist
You require a larger dose of buprenorphine compared to methadone
Patient is less likely to overdose on buprenorphine
Stem 2 - question 1 of 4
A 60 year old alcoholic is admitted to AMU after being found unconscious in his home. During his recovery he becomes highly agitated and reports seeing "pygmies fighting in the corridors".
What is the likely cause of these signs and symptoms?
Stem 2 - question 2What drug would you use to treat the condition described above?
Stem 2 - question 3What drug is used to prevent Wernicke-Korsakoff Sydrome?
Stem 2 - question 4The patient is eventually discharged from hospital but begins drinking again. After several months he speaks to his GP about getting help to treat his alcoholism. As part of this treatment, which drug would the patient be prescribed to manage the side effects of withdrawal?
Inhibits dopamine re-uptake
Monoamine oxidase inhibitor
Stimulates NMDA receptor
Prevents breakdown of acetylcholine
Stimulates release of histamine
- NICE Clinical Guideline 52: https://www.nice.org.uk/guidance/cg52/chapter/1-Guidance#pharmacological-interventions-in-opioid-detoxification, accessed 21 October 2020
- BNF’s Treatment Summary for Alcohol Dependence: https://bnf.nice.org.uk/treatment-summary/alcohol-dependence.html, accessed 21 October 2020
- Clark, T., Fergusson, E. and Day, E., 2017. Core Clinical Cases In Psychiatry. 2nd ed. Taylor and Francis Group.