Physiology of the Small Intestine MCQ
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The substance protecting the brush border of the small intestine is secreted by?
Which of the following describe a messenger of the small intestine?
Activation of the MMC
Direct activation of localised bowel autonomic plexuses
Direct activation of enteric nervous system plexuses
All of the above
Question 2 Explanation:
The answer is all of the above. We are referring to motilin, secreted by the small intestine and triggering the migrating motor complex via regulation of ANS and ENS plexuses
The major pancreatic duct ...
Is comprised of acid-secreting epithelium
Traverses the body of the pancreas and empties into Vater’s ampulla
Is upregulated by CCK only
Is downregulated in its secretions through cholinergic transmission
Which describes an arterial acidosis of the peri-ductular pancreatic vessels?
A normal process of secondary active transport of H+ from the lumen
A normal process of facilitated diffusion of H+ from the lumen
A highly proteinaceous diet is partly digested to smaller macromolecules by which luminal membrane enzyme?
In which of the following stages are fats held in micelles at the brush border?
During combination with phospholipids and bile salts
Secretion of bile salt
During digestion by pancreatic lipase
A lymphatic vessel is sampled for content of triacylglycerol. In which superstructure is this stored for lymphatic travel?
A GLUT5 deficiency would render which carbohydrate deficient in the serum?
By which form of movement does fructose enter the enterocyte?
Primary active transport
Secondary active transport
Which of the following groupings are not absorbed via receptor-mediated endocytosis?
Question 10 Explanation:
Free iron, in the Fe3+ form, is non absorbable and must be reduced by duodenal cytochrome B ferric reductase at the brush border before DMT1 allows its crossing into the enterocyte.
Which of the following causes anaemia from poorly controlled rheumatoid arthritis?
Question 11 Explanation:
Hepcidin is an acute phase protein (APP) released from hepatocytes in response to acute inflammation - and to further trigger the response. As part of its functionality, it downregulates the basolateral enterocyte transporter termed FP1 or ferroportin-1. Thus dietary absorbed iron cannot pass to the serum, and the patient results in hypochromic, microcytic anaemia of chronic disease.
A patient with acute pancreatitis will most likely present with ...
Both steatorrhea and flatus
Question 12 Explanation:
An inability to secrete pancreatic lipase leaves a proportion of luminal bolus fat as unabsorbed. Thus is defecated, forming “floating, pale” stools termed steatorrhoea.
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