😀 EASY
NeuroSoc and MedGuide hosted a fantastic, all-day neurophysiology session for phase I Warwick Medical Students (February 2021). In this day, we gave eight lectures covering many of the Brain and Behaviour Preclinical contents. Check out one of those lectures below. Enjoy!
Awaiting review
Neuro-Encrinology – available here
Movement Disorders – available here
Head Trauma and Consciousness – available here
Depression and Anxiety – available here
Dementia and Cognitive Assessment – available here
Pain and Analgesia – available here
CNS Infection – available here
Stroke – available here
Epilepsy – available here
Physiology day Pain and analgesia questions
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Question 1 |
Which of the following best describes the difference between nociceptive and neuropathic pain?
Nociceptive pain is a “top down” response from the cortex and Neuropathic pain is a “bottom up response to damage in the periphery/body” | |
Nociceptive pain occurs in response to proprioception and Neuropathic pain occurs in response to high temperatures | |
Nociceptive pain involves c fibres and is the quick type of pain and Neuropathic pain is a delta fibres and is the slow response to pain | |
Nociceptive pain occurs due to a response in inflammatory mediators around the neurons and Neuropathic pain signals damage to the neurons themselves |
Question 2 |
Which of the following is not an example of nociceptive pain?
Lower back pain | |
Arthritis | |
Visceral pain | |
Migraine |
Question 3 |
What is referred pain?
Pain that occurs when somatic and visceral pain signals merge at the same level/area in the spinal cord | |
Pain signals that occur as a failure of neuronal migration in development | |
Pain signals that radiate outward from the area of tissue damage | |
When the brain misinterprets a pain signal as coming from the central nervous system with one from the peripheral nervous system |
Question 4 |
Which of the following analgesics does not target the enzyme cyclooxygenase?
Ibuprofen | |
Paracetamol | |
Diclofenac | |
Naloxone |
Question 5 |
Which of the following is an example of the gate theory of pain?
Simultaneous mechanical input to a wounded area enhances pain as the simultaneous mechanotransmission gives off collaterals in the spinal cord that reduce pain tthreshold of neurons going to the brain | |
Proprioceptive input blocks pain signals travelling to the brain | |
Simultaneous mechanical input to a wounded area decreases pain as the simultaneous mechanotransmission gives off collaterals in the spinal cord that reduce pain transmission to the brain | |
Simultaneous neuropathic pain blocks nociceptive pain from reaching the spinal cord |
Question 6 |
Which of the following is an example of descending inhibition?
A patient takes ibuprofen for their back pain | |
A patient runs their stubbed toe | |
A patient feels better after psychological therapy and their chronic pain decreases in intensity | |
A patient goes to sleep to avoid their chronic pain |
Question 7 |
Which of the following drugs are not suitable for neuropathic pain?
Nortriptyline | |
Amitriptyline
| |
Aspirin | |
Gabapentin |
Question 8 |
Which of the following describes the third step in the WHO pain ladder?
Non-opioid
± adjuvant | |
Weak opioid
± non-opioid
± adjuvant
| |
Strong opioid
± non-opioid
± adjuvant
| |
Strong Opioid |
Question 9 |
Which of the following is not part of the mechanism of action of opioids?
Decreasing opening of voltage-dependent Ca2+ channels
| |
Decreasing Ca2+ release from intracellular stores | |
Decreasing exocytosis of transmitter vesicles
| |
Blocking Na+ ion flow |
Question 10 |
Which of the following is not an example of the main types of pain and treatment?
Referred Pain – treat underlying cause
| |
Neuropathic – antidepressants and antiepileptics
| |
Nociceptive – NSAIDs and opioids
| |
Opioid withdrawal - Naloxone |
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